Search on: GROWTH FACTOR RECEPTOR BOUND PROTEIN 10 
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Descriptor English:   GRB10 Adaptor Protein 
Descriptor Spanish:   Proteína Adaptadora GRB10 
Descriptor Portuguese:   Proteína Adaptadora GRB10 
Synonyms English:   GRB10 Protein
Maternally Expressed Gene 1 Protein
Growth Factor Receptor Bound Protein 10
Growth Factor Receptor-Bound Protein 10  
Tree Number:   D12.644.360.024.300
D12.776.157.057.029
D12.776.476.024.380
Definition English:   A binding partner for several RECEPTOR PROTEIN-TYROSINE KINASES, including INSULIN RECEPTOR and INSULIN-LIKE GROWTH FACTOR RECEPTOR. It contains a C-terminal SH2 DOMAIN and mediates various SIGNAL TRANSDUCTION pathways. 
History Note English:   2006(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50768 
Unique Identifier:   D051383 

Occurrence in VHL:
 

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